Wednesday, June 26, 2013

When AIDS viruses are transmitted despite treatment

June 24, 2013 ? While antiretroviral drugs offer an efficient means of preventing the replication of HIV in the blood, shedding of HIV may occur in semen, so that other persons can become infected during unprotected sexual intercourse. This occurs in particular if the male genital tract also has other viral infections.

That is the conclusion reached by a scientist who is supported by the Swiss National Science Foundation (SNSF).

In principle, modern combination therapies are very effective at keeping AIDS causative agents in check. The treatment usually leads to a situation in which there is no longer any evidence of Human-Immunodeficiency Viruses (HIV) in the body. In this way, the drugs can also reduce the disease transmission rate to just one tenth. So why do new infections occur despite treatment?

Sperm containing a cocktail of viruses

The answer, according to findings recently published by the Swiss researcher Sara Gianella Weibel and her American colleagues, is that other viruses also play a role. Working at the University of California in San Diego, the SNSF-funded scientist studied the semen of 114 HIV-infected men undergoing treatment who have sex with men. She found that the seminal fluid of 11 of the men contained a considerable quantity of HI viruses, even though the viral load of the blood of all of the men was very low. In eight of these 11 cases, Gianella Weibel also found evidence of various forms of herpes.

Locally activated immune system

Some of these herpes viruses, such as cytomegalovirus, often remain unnoticed. However, if the viruses infect the male genital tract, they locally activate the immune system. As a result, there is a build-up of immune cells, including those in which HIV replicate, in the genital area. "Our data suggests that we must also direct our focus towards other viruses, if we really want to interrupt the transmission of AIDS," explains Gianella Weibel.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/18ConyVEw8g/130624075731.htm

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Tuesday, June 25, 2013

Mid-range Acer Liquid E2 headed to Three UK

Liquid E2Three UK has announced that it'll be carrying Acer's latest mid-range Android offering, the Liquid E2. The 4.5-incher, which comes with a qHD (960x540) display resolution and a quad-core MediaTek 1.2GHz processor, will be arriving "soon," the network said in a media release today. Three says the Liquid E2 will run on Three's 42Mbps DC-HSDPA network, though it looks like support for the carrier's upcoming LTE support is out of the question.

Other notable specs include an 8-megapixel camera, stereo speakers, 1GB of RAM and 4GB of storage, expandable via microSD. No release date has been given for the Acer Liquid E2 on Three, though with the device appearing on Three's "Coming Soon" page today, a retail launch probably isn't too far off.

More: Three UK

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/VAhMzezkbBU/story01.htm

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Key vote on immigration set in Senate

(AP) ? The Senate is preparing for a crucial test vote on a measure boosting border security along the U.S.-Mexico border and opening the door to citizenship for millions.

Ahead of the vote set for Monday evening, around a dozen Republican lawmakers had already indicated support, setting up a solid bipartisan margin of victory within reach of the 70 votes supporters are hoping for. All 54 Senate Democrats are likely to vote yes.

The measure includes changes to the original border security provisions in the bill that would double the size of the U.S. Border Patrol at a cost of around $30 billion and complete 700 miles of fencing. That compromise emerged last week after secret negotiations between Republicans and Democrats aimed at bringing more Republican senators on board.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-06-24-Immigration/id-dca15cb4878f44e288620a5d9b1c12c2

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IFC books U.S. rights on Michael Winterbottom's 'The Trip to Italy'

By Brent Lang

LOS ANGELES (TheWrap.com) - IFC Films has acquired U.S. rights to "The Trip to Italy."

The film is Michael Winterbottom's follow-up to his 2010 road-trip comedy "The Trip," which IFC also released. The latest sight-seeing jaunt will reunite Steve Coogan and Rob Brydon and is in production in Italy.

The sequel finds Brydon commissioned by a newspaper to go on a driving tour of Italy to follow in the footsteps of seminal Romantic poets. Coogan becomes his wing-man for the journey. Hopefully they will rekindle their battling Michael Caine impressions - a highlight of the first film.

"The Trip" received generally favorable reviews when it debuted domestically and earned more than $2 million stateside.

The deal for "The Trip to Italy" was negotiated by Arianna Bocco, senior vice president of acquisitions and productions for Sundance Selects/IFC Films with GoalpostFilm on behalf of the filmmakers. Goalpost Film is handling international sales.

Source: http://news.yahoo.com/ifc-books-u-rights-michael-winterbottoms-trip-italy-191813904.html

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Monday, June 24, 2013

Highly Visual 2.0: A Mobile Reader for the Visually Minded

Highly Visual 2.0: A Mobile Reader for the Visually Minded

Especially with the upcoming demise of Google Reader, RSS alternatives abound. But how do you pick the one that's right for you from all the riff raff? Well, if you're someone who's feed tends to stick to the more image oriented, Highly Visual 2.0 may be exactly what you're looking for?at least in a mobile reader, that is.

What does it do?

Lets you browse your feed with a heavy focus on the images. Or rather?the entire focus is on the images. Zip through the articles in your feeds' by browsing rows of pictures alone. You can choose for Highly Visual to auto-populate a topic on its own, or you can create your a customized feed all your own. Click on the image to see the full post, and share the article on a variety of social media should the feeling strike.

Why do we like it?

With so many new readers coming out, they're all starting to look more or less the same. Highly Visual, though separates itself from the pack with a major focus on images. This is perfect for someone heavy into photography or wants to add some Pinterest appeal(?) to their RSS. Of course, if you use readers to, you know, read articles, this probably isn't going to be fore you.

But as a mobile app, it could still be a nice way to swipe through and get a very quick, if not entirely thorough view of what's going on in the world. Highly Visual has been around for a bit, sure but Version 2 has seen the grid rebuilt from the ground up, giving you a fun, beautiful, and slightly different break from your normal news consumption.

Highly Visual 2.0, Download this app for: iOS, $3

The Best: Beautiful, easy to browse layout

The Worst: Would benefit from marking things as read/unread

Source: http://gizmodo.com/highly-visual-2-0-a-mobile-reader-for-the-visually-min-564276655

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How Mi Voz mobilized 30,000 correspondents across Chile and ...

Photo: Courtesy of Mi Voz

Photo: Courtesy of Mi Voz

A Chilean community news network is succeeding on two fronts where countless online media projects fail: mobilizing ?citizen journalists? and actually making the venture profitable.

Mi Voz is a network of 20 media outlets that boasts a combined force of 30,000 ?citizen correspondents? from the Peruvian border in the north to Patagonia in the south. The volunteer contributors submit original stories, which are then vetted by professional editors. Of the 20 outlets, 16 are local dailies and four are topical magazines.? Together they bring in a combined traffic of 2.5 million unique visitors per month. Not bad in a nation of 17 million.

?We wanted to create a space where we could create something different ? a community public forum that could last over the long term,? said Paula Rojo, one of the project?s founders.

Eight years since launching, Mi Voz is bringing in $2 million yearly and does not rely upon foundation or government support. Its diverse business model came together four years after launching and combines traditional advertising with community outreach and research studies. The company employs both regional and national advertising ? including government agencies and local businesses. ?Sales have increased yearly, along with traffic.

Rojo, a designer by profession, said the initial goal was not to create a business, but to tell the stories from regions outside of Santiago which are rarely heard in Chile. The news coverage that did exist was generally about scandals or crime. In response, the network launched in 2005, after the co-founder Jorge Dom?nguez observed how Korea?s Oh My News?was activating residents to tell their own stories.

When Rojo and Dominguez shared their plan for a citizen news outlet with national networks, the response was that there was no way it could succeed without crime, sex, and scandal. But Mi Voz persevered, proving that people were interested in other types of stories and that such an enterprise could be lucrative.

?We want to create a space where citizens, leaders, and officials can converse and discuss the collective future of the city,? Rojo said.

The staff has grown to more than 50 people, about eight of whom work exclusively on the business side. A local editor is based in each city. In addition to vetting stories and working on copy, editors are also responsible for mobilizing and training residents and sometimes help by providing reporters a workspace with Internet capability.

Rojo said they have never received a complaint about the lack of pay from their contributors: ?They feel owners of the media,? she said. ?They can have influence.?

Participants of a Mi Voz training. | Photo: Courtesy of Mi Voz

Participants of a Mi Voz training. | Photo: Courtesy of Mi Voz

Part of Mi Voz?s philosophy is to not limit who is involved. They include submissions from public officials, representatives of community organizations, and even businesses right alongside reports from more objective ?citizen correspondents.? In an area where mining is controversial, for example, both the mining companies and residents opposed to the mining can post. The editor tries to facilitate discussion, however, and make sure that one voice does not dominate. ?We are interested in the conversation, the discussion,? Rojo said.

In the future, Rojo said, that online public forum may expand. She would not reveal where, but she said Mi Voz is now exploring ways to expand its forum for community correspondents and profitable business to other nations in Latin America.

Mi Voz is just one of many new journalism initiatives springing up across Latin America. In April, 14 initiatives from across South America and Spain participated in the Knight Center for Journalism in the Americas Ibero-American Colloquium on Digital Journalism.

Here are some of the other projects worth following:

Animal Politico
In three years, the Mexican online political site Animal Politico ? think part Politico, part Buzz Feed ? has grown to have the largest social media presence in Mexico, claiming more than 375,000 Twitter followers and 469,000 Facebook likes.

A P?blica?
A P?blica is a women-run investigative network based in Brazil. Similar to Center for Investigative Reporting or ProPublica, A P?blica makes an effort to partner with publications on stories to hit a larger audience. CIPER Chile ?and IDL-Reporteros?in Peru are two similar investigative networks.

Anfibia and Plaza P?blica
Some Latin American universities are supporting new sites that do insight and investigative reporting. ?Anfibia, from the National San Mart?n University in Buenos Aires, Argentina, was created in an attempt to translate academic research and language to the larger communities. Plaza P?blica, from Guatemala, is affiliated with the University Rafael Land?var in Guatemala City, which invited a ?group of journalists to create a digital media that supported the construction and defense of a solid democracy.?

Source: http://www.ojr.org/how-mi-voz-mobilized-30000-correspondents-across-chile-and-created-a-sustainable-business-model/?utm_source=rss&utm_medium=rss&utm_campaign=how-mi-voz-mobilized-30000-correspondents-across-chile-and-created-a-sustainable-business-model

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Robo-pets may contribute to quality of life for those with dementia

June 24, 2013 ? Robotic animals can help to improve the quality of life for people with dementia, according to new research.

A study has found that interacting with a therapeutic robot companion made people with mid- to late-stage dementia less anxious and also had a positive influence on their quality of life.

The pilot study, a collaboration led by Professor Wendy Moyle from Griffith University, Australia and involving Northumbria University's Professor Glenda Cook and researchers from institutions in Germany, investigated the effect of interacting with PARO -- a robotic harp seal -- compared with participation in a reading group. The study built on Professor Cook's previous ethnographic work carried out in care homes in North East England.

PARO is fitted with artificial intelligence software and tactile sensors that allow it to respond to touch and sound. It can show emotions such as surprise, happiness and anger, can learn its own name and learns to respond to words that its owner uses frequently.

Eighteen participants, living in a residential aged care facility in Queensland, Australia, took part in activities with PARO for five weeks and also participated in a control reading group activity for the same period. Following both trial periods the impact was assessed, using recognised clinical dementia measurements, for how the activities had influenced the participants' quality of life, tendency to wander, level of apathy, levels of depression and anxiety ratings.

The findings indicated that the robots had a positive, clinically meaningful influence on quality of life, increased levels of pleasure and also reduced displays of anxiety.

Research has already shown that interaction with animals can have a beneficial effect on older adults, increasing their social behaviour and verbal interaction and decreasing feelings of loneliness. However, the presence of animals in residential care home settings can place residents at risk of infection or injury and create additional duties for nursing staff.

This latest study suggests that PARO companions elicit a similar response and could potentially be used in residential settings to help reduce some of the symptoms -- such as agitation, aggression, isolation and loneliness -- of dementia.

Prof Cook, Professor of Nursing at Northumbria University, said: "Our study provides important preliminary support for the idea that robots may present a supplement to activities currently in use and could enhance the life of older adults as therapeutic companions and, in particular, for those with moderate or severe cognitive impairment.

"There is a need for further research, with a larger sample size, and an argument for investing in interventions such as PARO robots which may reduce dementia-related behaviours that make the provision of care challenging as well as costly due to increased use of staff resources and pharmaceutical treatment."

The researchers of the pilot study have identified the need to undertake a larger trial in order to increase the data available. Future studies will also compare the effect of the robot companions with live animals.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/jFB6Ff3OGnY/130624075748.htm

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